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Emergency Professionals

Podcast #226 - 10 Key Points from the CDC's Update on Gonorrhea Management

1/12/2021

3 Comments

 
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Recently, the Centers for Disease Control (CDC) released updated guidelines for treating gonococcal infections.  Given the increase in antibiotic resistance, this provides an important change in the recommended management for not only gonorrhea but also chlamydia.  
To see the full updated guidelines follow THIS LINK.  However, we will summarize the key updates here:
  1. For uncomplicated gonococcal infections of the cervix, urethra, or rectum treat with a single dose of ceftriaxone 500 mg intramuscularly (IM) and 1 gram if the patient weighs 150 kg or more.
  2. When ceftriaxone cannot be used due to an allergy, gentamicin 240 mg IM and azithromycin 2 grams orally should be given.
  3. Alternatively, if ceftriaxone is not available, cefixime 800 mg orally may be given.
  4. Cefixime should not be routinely used because it does not provide as high, or as sustained, bactericidal blood levels as ceftriaxone.
  5. There is no reliable alternative treatments to pharyngeal gonorrhea and those with a reported beta-lactam (especially ceftriaxone) allergy should be more thoroughly evaluated for anaphylaxis or other severe reaction such as Stevens-Johnson Syndrome (SJS).
  6. In all forms of uncomplicated gonococcal infection (cervix, urethra, rectum, or pharyngeal), if chlamydia has not been excluded treat with doxycycline 100 mg orally twice daily for 7 days.
  7. Azithromycin is no longer recommended for routine use due to significantly increasing resistance.
  8. However, in pregnancy,  1 gram of azithromycin orally may be used to treat chlamydia.
  9. In cases where the law permits it, expedited partner treatment should be cefixime 800 mg once orally and doxycycline 100 mg orally twice daily  for 7 days.
  10. A test of cure is recommended for pharyngeal gonorrhea 7-14 days after the initial treatment regardless of what antibiotic regimen is used.

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3 Comments
Lucy Eagleston
6/19/2025 05:17:49 am

Hello everyone, I wanted to share my personal experience regarding herpes, as it may help someone facing a similar situation. A few years ago, I was diagnosed with herpes. Hearing that news felt overwhelming and isolating. I spent a lot of time searching for answers, reading different opinions, and trying to find something that could help me feel hopeful again.
During my search, a friend introduced me to an herbal doctor named Dr. Utu. They told me about his natural approach to permanently curing herpes using plant-based remedies. I was skeptical at first, but also curious and open to alternative healing methods, especially those based on herbs and nature. After talking to him, I decided to give his treatment a try.
He sent me an herbal remedy, and I followed the instructions strictly. To my surprise, within a month, I started noticing changes. I felt better physically, and the symptoms I used to struggle with began to disappear. Out of caution, I went for multiple lab tests after the treatment and each one came back negative.
Anyone can reach out to Dr. Utu directly at [email protected]

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Athony Isak
6/21/2025 09:15:32 am

My heart is so filled with joy. If you are suffering from Erectile dysfunction or any other disease you can contact Dr. Moses Buba on this [email protected] or His website : https://www.facebook.com/profile.php?id=61559577240930 . For more information from me reach me via WhatsApp : +44 7375 301397

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Cheryl D Bayerl
7/4/2025 02:46:31 pm

I'm excited to share my incredible herpes journey here!
After many years of ineffective medical treatments, countless prayers, and fasting, God led me to Dr. Utu's herbal cure.
I stumbled upon Dr. Utu's African traditional herbal remedies online, and people's positive testimonials gave me hope.
I reached out to him, ordered the herbal cure, and he guided me through the process.
After 4 weeks of treatment, I was completely cured of both HSV 1 and HSV 2. Hospital tests confirmed I'm herpes free!
I retested 2 months later at another hospital, and the results were still negative!
Dr. Utu's herbal cure changed my life, restoring my health and dignity. I'm forever grateful and urge anyone struggling with herpes to contact him for their own herbal cure. His remedies truly work!
Anyone can reach Dr. Utu via email at [email protected]

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