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Emergency Professionals

Podcast #229 - COVID-19 Variants and the Impact on Vaccinations

2/2/2021

3 Comments

 
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We received quite a bit of feedback with the last podcast and requests to discuss specifically the variants and their potential impacts on the current COVID-19 vaccines.  It is worth noting that at the time of this publication there is still limited data but we discuss the key concepts and takeaways with the current knowledge we have on the topic.
First, we must remember that viruses mutate frequently.  COVID-19 is no different.  When vaccines are made, they are designed to have a broad net of coverage.  Viruses mutate frequently, but some are better at survival than others and may have the benefit (for the virus) of being more infectious which leads to further spread.  The current vaccines focus on the spike protein which provides a rather large net to help even when there are mutations.  As long as there is not a significant mutation that gets around the net of the vaccine, they should still be effective.

One example comes with the variants seen coming from the United Kingdom and South Africa that share the spike N501Y substitution.  A small (and preliminary, not yet peer-reviewed) study is available preprint on January 7, 2021 that helps demonstrate that these mutations are still covered under the net of Pfizer-BioNTech vaccine.  For now, continued use of the current vaccines is important to help stop the spread of COVID-19.

While the CDC has been attempting to track emerging variant cases in the United States, it is not being done consistently enough to be truly accurate.  The three main variants are B.1.1.7 from the UK, B.1.351 from South Africa, and P.1 from Brazil.  Currently, there is concern of a potential "escape mutation" with one strain named E484K.  This sounds scary because an escape mutation can slip from underneath the safety net a vaccine offers.  However, this has not been truly confirmed. It also does not mean that the vaccine will be completely useless, but more likely will be less effective.  Fortunately, with the current vaccines they can be reworked in about 4-6 weeks to cover such mutations and extend the net.  These are often the same kinds of modifications that are made when we have our seasonal influenza vaccines that have some variations.  Still safe and effective like the original vaccine produced.
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There are some great epidemiologists that have taken to social media to help describe and discuss some of these important concepts.  One called "Your local epidemiologist" (Dr. Katelyn Jetelina) created the graphic above which is up-to-date at this time covering the pertinent details with the main vaccines out there and overall effectiveness.  "Friendly Neighbor Epidemiologist" (Dr. Emily Smith) is another great source to find on social media.

Let us know what you think by giving us feedback here in the comments section or contacting us on Twitter or Facebook.  Remember to look us up on Libsyn and on Apple Podcasts.  If you have any questions you can also comment below, email at [email protected], or send a message from the page.  We hope to talk to everyone again soon.  Until then, continue to provide total care everywhere.
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3 Comments
Lucy Eagleston
6/19/2025 03:53:59 am

Hello everyone, I wanted to share my personal experience regarding herpes, as it may help someone facing a similar situation. A few years ago, I was diagnosed with herpes. Hearing that news felt overwhelming and isolating. I spent a lot of time searching for answers, reading different opinions, and trying to find something that could help me feel hopeful again.
During my search, a friend introduced me to an herbal doctor named Dr. Utu. They told me about his natural approach to permanently curing herpes using plant-based remedies. I was skeptical at first, but also curious and open to alternative healing methods, especially those based on herbs and nature. After talking to him, I decided to give his treatment a try.
He sent me an herbal remedy, and I followed the instructions strictly. To my surprise, within a month, I started noticing changes. I felt better physically, and the symptoms I used to struggle with began to disappear. Out of caution, I went for multiple lab tests after the treatment and each one came back negative.
Anyone can reach out to Dr. Utu directly at [email protected]

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Athony Isak
6/21/2025 09:09:49 am

My heart is so filled with joy. If you are suffering from Erectile dysfunction or any other disease you can contact Dr. Moses Buba on this [email protected] or His website : https://www.facebook.com/profile.php?id=61559577240930 . For more information from me reach me via WhatsApp : +44 7375 301397

Reply
Cheryl D Bayerl
7/4/2025 02:40:35 pm

I'm excited to share my incredible herpes journey here!
After many years of ineffective medical treatments, countless prayers, and fasting, God led me to Dr. Utu's herbal cure.
I stumbled upon Dr. Utu's African traditional herbal remedies online, and people's positive testimonials gave me hope.
I reached out to him, ordered the herbal cure, and he guided me through the process.
After 4 weeks of treatment, I was completely cured of both HSV 1 and HSV 2. Hospital tests confirmed I'm herpes free!
I retested 2 months later at another hospital, and the results were still negative!
Dr. Utu's herbal cure changed my life, restoring my health and dignity. I'm forever grateful and urge anyone struggling with herpes to contact him for their own herbal cure. His remedies truly work!
Anyone can reach Dr. Utu via email at [email protected]

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